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Microbiologist nPOC Operational Feasibility Study, William J. Clinton Foundation (WJCF), Ahmedabad

Author : India Water Portal

WJCF is an Indian non-profit organisation committed to saving lives by reducing the burden of disease and strengthening government-owned, high-quality health systems. Since 2007, WJCF has combined data-driven approaches and deep public health expertise with strong government partnerships to design, implement, and scale solutions across India’s national and state health programmes. We work for and at the service of governments — supporting the Ministry of Health & Family Welfare and State Departments of Health to build systems that are strong, sustainable, and led by Indian institutions.

As an Indian organisation, WJCF brings an unmatched depth of contextual understanding of India’s health system architecture, policy landscape, and implementation realities across diverse geographies and population groups. This local institutional credibility, combined with global technical rigour, is central to WJCF’s effectiveness as a partner to governments and donors.

Our work is built around four complementary roles: as a Trusted Government Partner, co-designing programmes and strengthening health system architecture; as an Operational Partner, translating strategies into effective on-the-ground delivery; as a Market Shaper, improving the availability and affordability of health commodities; and as an Ecosystem Catalyst, convening governments, development partners, academia, and the private sector to drive solutions at scale.

WJCF’s programme portfolio spans thematic areas like hepatitis, HIV/AIDS, tuberculosis, vector-borne diseases), syphilis, cervical cancer, diabetes, maternal and childhood anaemia, immunisation, under-5 diarrhoea and pneumonia, sexual and reproductive health, Ayushman Bharat Pradhan Mantri – Jan Arogya Yojana (AB PM-JAY), Ayushman Bharat Digital Mission (ABDM), hypoxemia and oxygen, safe drinking water, sickle cell disease, presbyopia, lead poisoning, and cross cutting thematic areas like AI and Health, integrated disease surveillance, and climate and health.

We currently support programmes across 19 states and union territories, with teams working at national, state, district, and sub-district levels.

Our people are our greatest asset. WJCF brings together a talented, diverse team of professionals from public health, analytics, consulting, healthcare, the development sector, and academia, all united by a shared commitment to improving health outcomes for the people of India. We are entrepreneurial, action-oriented, and deeply grounded in the communities and systems we work in. Our field teams collectively bring hundreds of years of experience managing public health programmes across the country.

WJCF collaborates with a range of international and domestic partners and donors to advance its mission, including an affiliation with the Clinton Health Access Initiative (CHAI), a global health organisation with which WJCF shares a common mission and values.

About the Program:

The National TB Elimination Programme (NTEP), led by the Central TB Division (CTD), MoHFW, is working towards TB elimination in line with the Sustainable Development Goals. WJCF has supported the CTD and more than fifteen state health departments on TB programming since 2012, with interventions across preventive therapies, case detection, diagnostics access, private-sector engagement, strategic planning, and service delivery

About the Project:

More than half of all people with TB in India first seek care from private providers, yet private-sector notifications account for only about one-third of total cases. A key driver of this gap is the limited availability of WHO-recommended rapid molecular diagnostics in private clinics. Existing platforms like GeneXpert and Truenat, though accurate, require dedicated infrastructure, stable power, and high per-test costs, making them unsuitable for routine point-of-care use. This leads to referrals and significant drop-outs along the diagnostic cascade.

The Huwel UniAmp NAT Device (Huwel Lifesciences, Telangana) is a palm-sized, battery-operated, isothermal amplification platform validated by ICMR for near point-of-care (nPOC) TB testing. Paired with the Quantiplus® MTB FAST cartridge, it delivers MTB-Detected/Not Detected results in 35–60 minutes. It is currently the only ICMR-validated indigenous nPOC NAT system, significantly more affordable than existing platforms, and works with both sputum and tongue swabs.

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